Sex-specific presentation, care, and clinical events in individuals admitted with NSTEMI: the ACVC-EAPCI EORP NSTEMI registry of the European Society of Cardiology
Authors' conclusion
In contemporary practice, women presenting with NSTEMI, compared with men, less frequently receive antiplatelet prescription, smoking cessation advice, or are considered eligible for ICA.
Study context
- Population
- Patients admitted with type I NSTEMI, ACVC-EAPCI EORP NSTEMI registry of the ESC
- Participants
- 2,947 patients
- Exposure
- Women vs men
- Womenn = 907
- Menn = 2,040reference
- Outcome
- Quality of care (12 guideline-recommended interventions; all-or-none composite for optimal care) and outcomes (in-hospital acute HF, cardiogenic shock, repeat MI, stroke/TIA, BARC type ≥3 bleeding or death; 30-day mortality)
Methodological detailsmulticentre, 287 centres in 59 countries
- Multicentre
- 287 centres in 59 countries
Main finding
As reported in the abstract
Care interventions
Invasive coronary angiography
P < 0.001
Smoking cessation advice
P < 0.001
P2Y12 inhibitor at discharge
P < 0.001
Observational data: associations, not effects.
Further findings
Baseline risk (GRACE >140; CRUSADE >40)
GRACE >140
CRUSADE >40
Non-receipt of ICA due to frailty
P = 0.010
Non-obstructive CAD or angiographically normal arteries at ICA
P < 0.001
- Baseline risk (GRACE >140; CRUSADE >40): GRACE P < 0.001
- Baseline risk (GRACE >140; CRUSADE >40): CRUSADE P < 0.001
Original publication
Sex-specific presentation, care, and clinical events in individuals admitted with NSTEMI: the ACVC-EAPCI EORP NSTEMI registry of the European Society of Cardiology. Eur Heart J Acute Cardiovasc Care. Published 31 October 2023. doi:10. 1093/ ehjacc/ zuad134
Summarised from the published abstract; every number is checked against it