Coronary disease & ACS

Sex-specific presentation, care, and clinical events in individuals admitted with NSTEMI: the ACVC-EAPCI EORP NSTEMI registry of the European Society of Cardiology

Eur Heart J Acute Cardiovasc CarePublished Prospective cohort study

Authors' conclusion

In contemporary practice, women presenting with NSTEMI, compared with men, less frequently receive antiplatelet prescription, smoking cessation advice, or are considered eligible for ICA.

Study context

Population
Patients admitted with type I NSTEMI, ACVC-EAPCI EORP NSTEMI registry of the ESC
Participants
2,947 patients
Exposure
Women vs men
  • Womenn = 907
  • Menn = 2,040reference
Outcome
Quality of care (12 guideline-recommended interventions; all-or-none composite for optimal care) and outcomes (in-hospital acute HF, cardiogenic shock, repeat MI, stroke/TIA, BARC type ≥3 bleeding or death; 30-day mortality)
Methodological detailsmulticentre, 287 centres in 59 countries
  • Multicentre
  • 287 centres in 59 countries

Main finding

As reported in the abstract

Care interventions

Invasive coronary angiography

P < 0.001

Smoking cessation advice

P < 0.001

P2Y12 inhibitor at discharge

P < 0.001

Observational data: associations, not effects.

Further findings

Baseline risk (GRACE >140; CRUSADE >40)

GRACE >140

CRUSADE >40

Non-receipt of ICA due to frailty

P = 0.010

Non-obstructive CAD or angiographically normal arteries at ICA

P < 0.001

  • Baseline risk (GRACE >140; CRUSADE >40): GRACE P < 0.001
  • Baseline risk (GRACE >140; CRUSADE >40): CRUSADE P < 0.001

Original publication

Sex-specific presentation, care, and clinical events in individuals admitted with NSTEMI: the ACVC-EAPCI EORP NSTEMI registry of the European Society of Cardiology. Eur Heart J Acute Cardiovasc Care. Published 31 October 2023. doi:10.1093/ehjacc/zuad134

Summarised from the published abstract; every number is checked against it

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