Heart failure & cardiomyopathies

Diagnostic and Therapeutic Practice for Heart Failure with Preserved Ejection Fraction (HFpEF) Across Continents and Regions: An International Survey

ESC Heart FailPublished Cross-sectional study

Authors' conclusion

There are considerable global variations in the diagnosis and management of HFpEF. Most physicians favour SGLT2i despite regional disparities in health care resources and guideline adherence.

Study context

Population
Physicians (cardiologists and non-cardiologists) from 91 countries managing HFpEF, surveyed 1 May–1 July 2023
Participants
1,459 physicians91 countries
Exposure
Cardiologists vs Non-cardiologists
  • Cardiologistsn = 1,242
  • Non-cardiologistsn = 217
Outcome
Worldwide variations in diagnosis and treatment of HFpEF
Methodological detailsinternational web-based survey, Mean age of respondents 42 (34-49) years; 61% male
  • International web-based survey
  • Mean age of respondents 42 (34-49) years; 61% male

Main finding

As reported in the abstract

HFpEF defined as LVEF ≥50%
89.2%
Significant regional variations in HFpEF management
P < 0.001
HFpEF patients managed by cardiologists overall (significant regional variability)
63.1%
Natriuretic peptide use, Africa
70%-74%
Natriuretic peptide use, Southern/Western Europe
95%-97%
Diastolic stress testing, South-Eastern Asia
47%
Diastolic stress testing, elsewhere
13-36%
HFpEF scoring systems, South-Eastern Asia
78%
HFpEF scoring systems, Africa
30.1%
Always routine angiograms, Eastern Asia
52%
Always routine angiograms, Northern Europe
12%
SGLT2i preferred first-line treatment (across regions), followed by diuretics
45%-70%
Ideal setting: primarily SGLT2i
52%
Ideal setting: loop diuretics
33%
Ideal setting: beta-blockers
22%
SGLT2i availability (most available, overall)
88%
ARNI availability (least available)
61%
Multidisciplinary HF programmes, Asia
70%
Multidisciplinary HF programmes, Africa
24%

Observational data: associations, not effects.

Original publication

Diagnostic and Therapeutic Practice for HFpEF Across Continents and Regions: An International Survey. ESC Heart Fail. Published 1 October 2024. doi:10.1002/ehf2.15084

Composed by AI from the published abstract and checked against it. How Briefs are made →

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