Heart failure & cardiomyopathies

Physician Perceptions, Attitudes, and Strategies Towards Implementing Guideline-Directed Medical Therapy in Heart Failure with Reduced Ejection Fraction. A Survey of the Heart Failure Association of the ESC and the ESC Council for Cardiology Practice

Eur J Heart FailPublished Cross-sectional study

Authors' conclusion

Although comfort with implementing all four core drug classes in patients with HFrEF was high among physicians, a majority estimated implementation of GDMT in HFrEF to be low.

Study context

Population
Physicians with an interest in heart failure (HF), 91 countries
Participants
432 physicians91 countries
Outcome
Perceived comfort with implementing HFrEF guideline recommendations, guideline-directed medical therapy (GDMT) implementation status, sequencing strategies, and barriers
Methodological detailssurvey, 26-question survey disseminated via bulletin, e-mail and social channels
  • Survey
  • 26-question survey disseminated via bulletin, e-mail and social channels

Main finding

As reported in the abstract

Overall comfort with implementing quadruple therapy
87%
Estimated that >90% of HFrEF patients without contraindications received quadruple therapy
12%
Estimated time to initiate quadruple therapy: 1-2 weeks
34%
Estimated time to initiate quadruple therapy: 1 month
36%
Estimated time to initiate quadruple therapy: 3 months
24%
Estimated time to initiate quadruple therapy: ≥6 months
6%
Perceived clinical barrier: hypotension
70%
Perceived clinical barrier: creatinine increase
47%
Perceived clinical barrier: hyperkalaemia
45%
Perceived clinical barrier: patient adherence
42%

Observational data: associations, not effects.

Original publication

Physician Perceptions, Attitudes, and Strategies Towards Implementing Guideline-Directed Medical Therapy in Heart Failure with Reduced Ejection Fraction. A Survey of the Heart Failure Association of the ESC and the ESC Council for Cardiology Practice. Eur J Heart Fail. Published 22 March 2024. doi:10.1002/ejhf.3214

Composed by AI from the published abstract and checked against it. How Briefs are made →

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