Arrhythmias & electrophysiology

Diagnostic, pharmacological, and ablation approaches for idiopathic ventricular fibrillation: the 2024 European Heart Rhythm Association survey

EuropacePublished Cross-sectional study

Authors' conclusion

This survey highlights a significant heterogeneity of the diagnostic approach to IVF with underuse of crucial examinations. In line with guideline recommendation, drug therapy is more often considered as first-line therapy and ablation as second-line therapy for recurrent ICD shocks. However, quinidine is considered as drug of choice by <25% of respondents.

Study context

Population
Physicians across European Society of Cardiology (ESC) countries managing idiopathic VF (idiopathic ventricular fibrillation (IVF))
Participants
206 physicians · 41 countries
Outcome
Current practice in diagnostic assessment and therapeutic management of IVF and adherence to 2022 ESC guidelines
Methodological detailsphysician-based survey, online 24-item questionnaire, European Heart Rhythm Association (EHRA)
  • Physician-based survey
  • Online 24-item questionnaire
  • EHRA

Main finding

As reported in the abstract

Full diagnostic assessment of IVF (coronary angiogram/cardiac CT, ECG monitoring, exercise stress test, pharmacological challenges, CMR)
71 (35%)
CMR
51%
Sodium channel blocker test
34%
Genetic testing
43%
Preferred first-line strategy for recurrent implantable cardioverter-defibrillator (ICD) shocks: drug therapy
88%
Preferred strategy after first-line failure: ablation
53%

Observational data: associations, not effects.

Original publication

Diagnostic, pharmacological, and ablation approaches for idiopathic ventricular fibrillation: the 2024 European Heart Rhythm Association survey. Europace. Published 21 May 2025. doi:10.1093/europace/euaf049

Summarised from the published abstract; every number is checked against it

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