Acute cardiac care & resuscitation
Differential Effect of Left Ventricular Unloading According to the Aetiology of Cardiogenic Shock
Authors' conclusion
LV unloading with VA-ECMO may reduce 90-day mortality compared with VA-ECMO alone in patients with non-AMI-induced CS, but not in AMI-induced CS.
Study context
- Population
- Patients with cardiogenic shock undergoing venoaterial extracorporeal membrane oxygenation (VA-ECMO), January 2011 to March 2019; Acute myocardial infarction (AMI)-induced cardiogenic shock (CS) and non-AMI-induced CS71 AMI-induced, 57 non-AMI-induced CS · AMI-induced CS 71 · non-AMI-induced CS 57
- Participants
- 128 patients
- Exposure
- Left ventricular (LV) unloading with VA-ECMO vs VA-ECMO alone, by aetiology of cardiogenic shock (AMI vs non-AMI)
- Outcome
- Mortality
- Follow-up
- 90 days
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
90-day mortality, by CS aetiology
LV unloading vs VA-ECMO aloneAdjusted hazard ratio (95% CI)P value
AMI-induced CS
1.96(0.90–4.27)
P = 0.089non-AMI-induced CS
0.37(0.14–0.96)
P = 0.041Observational data: associations, not effects.
Original publication
Differential Effect of Left Ventricular Unloading According to the Aetiology of Cardiogenic Shock. ESC Heart Fail. Published 27 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →