Arrhythmias & electrophysiology

Differential Pacing Maneuver From the Vein of Marshall

Circ Arrhythm ElectrophysiolPublished Diagnostic study of an electrophysiological pacing maneuver

Authors' conclusion

Differential VOM pacing maneuver reflects the VOM conduction status. This maneuver can uncover residual epicardial connections that are missing with CS pacing.

Study context

Population
Patients undergoing radiofrequency and vein of Marshall (VOM) ethanol mitral isthmus ablation with a VOM electrode catheter
Participants
50 patients
Comparison
Differential VOM pacing vs conventional coronary sinus (CS) pacing for verification of mitral isthmus block
  • Residual VOM connectionn = 11
  • VOM blockn = 30reference
Outcome
Differential VOM pacing in patients with complete MI block by CS pacing

Performance

As reported in the abstract

Test or modelValueDistal minus proximal VOM pacing interval (longer)Distal vs proximal VOM pacing interval (shorter)
VOM block73%11±5 ms
Residual VOM connection27%16±8 ms

Value

VOM block73%
Residual VOM connection27%

Distal minus proximal VOM pacing interval (longer)

VOM block11±5 ms
Residual VOM connection— not stated in the abstract

Distal vs proximal VOM pacing interval (shorter)

VOM block— not stated in the abstract
Residual VOM connection16±8 ms
Incomplete mitral isthmus (MI) ablation by CS pacing; analysis indicated persistent VOM connection
9 patients

Further findings

Conduction time across the line, in patients with complete MI block by CS pacing

P < 0.01

  • Conduction time across the line, in patients with complete MI block by CS pacing: significantly shorter in the 11 patients with residual VOM connection

Reevaluation after VOM ethanol and further radiofrequency ablation of the connection

Successful reevaluated analyses indicating VOM block achievement
10

Original publication

Differential Pacing Maneuver From the Vein of Marshall. Circ Arrhythm Electrophysiol. Published 23 February 2024. doi:10.1161/circep.123.012420

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