Heart failure & cardiomyopathies
Digital Implementation Strategy to Increase SGLT2 Inhibitor Uptake in Heart Failure: Study Design of EMAIL-HF
Authors' conclusion
EMAIL-HF will determine whether a population-wide digital strategy can increase and accelerate guideline-based initiation of SGLT2 inhibitors in patients with chronic HF.
Study context
- Population
- Patients with heart failure (HF) diagnosed within the last 10 years, not treated with SGLT2 inhibitors, Capital Region of Denmark and Roskildedesign paper
- Participants
- 5,996 patients
- Comparison
- Digital letter on SGLT2 inhibitors with invitation for evaluation vs usual care
- Interventionn = 2,979
- Controln = 3,017reference
- Primary endpoint
- Proportion of patients initiating SGLT2 inhibitor therapy
- Follow-up
- Within 6 months after randomization
Methodological detailspragmatic, registry-based
- Pragmatic
- Registry-based
Primary result
As reported in the abstract
- Outcomes will be reported after completion of event accrual
Original publication
Digital Implementation Strategy to Increase SGLT2 Inhibitor Uptake in Heart Failure: Study Design of EMAIL-HF. ESC Heart Fail. Published 25 August 2025. doi:10. 1002/ ehf2. 15398
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