Heart failure & cardiomyopathies

Disparities in donor heart acceptance between the USA and Europe: clinical implications

Eur Heart JPublished Retrospective cohort study

Authors' conclusion

Eurotransplant countries exhibit more liberal donor heart acceptance practices than the USA.

Study context

Population
Adult reported heart donors, 2010–2020
Participants
8,714 vs 60,882
Exposure
Eurotransplant vs USA donor heart acceptance
  • Eurotransplantn = 8,714
  • USAn = 60,882reference
Outcome
Donor utilization (percentage of reported donors accepted for HT)
Methodological detailsregistry comparison
  • Registry comparison

Main finding

As reported in the abstract

Donor utilization

Observational data: associations, not effects.

Further findings

Predictors of donor non-acceptance

Donor age, smoking history and DM predicted non-acceptance in the USA and, by a lesser magnitude, in Eurotransplant
Donor obesity and hypertension predicted non-acceptance in the USA only

Estimated additional US heart transplant (HTs) with Eurotransplant-level utilization among top 30%-50% of donors (by quality) · annually

Additional US HTs annually
506-930

Original publication

Disparities in donor heart acceptance between the USA and Europe: clinical implications. Eur Heart J. Published 4 November 2023. doi:10.1093/eurheartj/ehad684

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