Coronary disease & ACS

Distal versus conventional transradial artery access for coronary catheterization in patients with ST- elevation myocardial infraction (STEMI) (DR-STEMI): Rationale and design of an international, multicenter, randomized trial

Am Heart JPublished prospective, open label, European, multicenter randomized-control trial

Study context

Population
Patients with STEMI undergoing coronary angiography and interventionsplanned enrollment (277 patients in each treatment arm)
Participants
554 patients
Planned comparison
Distal transradial access (dTRA) versus conventional transradial access (TRA) access in patients with STEMI undergoing coronary angiography and interventions
  • dTRAn = 277
  • TRAn = 277
Primary endpoint
Needle-to-wire time (time between the puncture of the radial artery and wire crossing of the infarct-related artery); noninferiority of dTRA to conventional TRA
Methodological details1:1 randomization, all-comers screening
  • 1:1 randomization
  • All-comers screening

No results yet. This paper sets out the design of a trial; its results are to come.

Further findings

Enrollment status · as of April 15th, 2025

Patients enrolled
309
Enrollment began
May 2024
Recruitment expected to continue
≈12 months

Original publication

Distal versus conventional transradial artery access for coronary catheterization in patients with STEMI (DR-STEMI): Rationale and design of an international, multicenter, randomized trial. Am Heart J. Published 13 August 2025. doi:10.1016/j.ahj.2025.08.007

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