Arrhythmias & electrophysiology
Durability of Pulmonary Vein Isolation Using Pulsed-Field Ablation: Results From the Multicenter EU-PORIA Registry
Authors' conclusion
In 144 patients with arrhythmia recurrence after PFA PVI, durable isolation was observed in 71% of the pulmonary veins during the redo procedure, and 38% of all patients showed durable isolation of all veins.
Study context
- Population
- Patients with arrhythmia recurrence undergoing clinically indicated left atrial redo procedure after index pulmonary vein isolation (PVI) using pulsed-field ablation (PFA)redo cohort of 1,184 index PFA patients
- Participants
- 144 patients
- Outcome
- PVI durability on per-vein and per-patient level (3-dimensional electroanatomical mapping)
Methodological detailsretrospective analysis of clinically indicated redo procedures, 7 European centres, EU-PORIA registry
- Retrospective analysis of clinically indicated redo procedures
- 7 European centres
- EU-PORIA registry
Main finding
As reported in the abstract
Pulmonary veins with durable isolation
404 of 567
71%
Patients with all pulmonary veins durably isolated
54
38%
Observational data: associations, not effects.
Further findings
Per-vein PVI durability by prior operator experience (cryoballoon vs only point-by-point radiofrequency)
- Higher durability with prior cryoballoon experience vs only point-by-point radiofrequency experience
- 76% vs 60%; P < 0.001
Lesion durability by cumulative operator AF ablation experience (≤5 vs >5 years) and PFA device size (31 mm vs 35 mm)
- No impact on lesion durability
- both P > 0.50
Arrhythmia recurrence after index PFA PVI
- Arrhythmia recurrence
- 272 (23%)
- Underwent left atrial redo procedure
- 144 (53%)
Original publication
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