Heart failure & cardiomyopathies
EARTH-HCM: A Real-World Tool to Visualize the Burden of Hypertrophic Cardiomyopathy in the United States
Authors' conclusion
EARTH-HCM demonstrates the feasibility of a national real-world surveillance framework to visualize the geographic distribution and healthcare burden of HCM and support future clinical and economic outcomes research.
Study context
- Population
- Patients with a diagnosis for hypertrophic cardiomyopathy (HCM) in US claims data, 2016 to 2023patients with a diagnosis for HCM
- Participants
- 431,457 patients
- Exposure
- oHCM vs nHCM
- oHCMn = 166,081
- nHCMn = 265,376
- Outcome
- Patient characteristics
Methodological detailsopen access, education tool
- Open access, education tool
Main finding
As reported in the abstract
- Male
- 51.1%
- Mean age
- 60.1 (17.7) years
- Median follow-up
- 3.0 (2.4) years
- Age 65+
- 53.4%
- Age 55-64
- 20.5%
- Resided in the South
- 36.3%
- Resided in the Northeast
- 24.8%
- Resided in the Midwest
- 24.3%
- Resided in the West
- 14.6%
Observational data: associations, not effects.
Original publication
EARTH-HCM: A Real-World Tool to Visualize the Burden of Hypertrophic Cardiomyopathy in the United States. ESC Heart Fail. Published 7 October 2026. doi:10.
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