Coronary disease & ACS

The European bifurcation club randomized trial of stepwise provisional stenting vs drug-coated balloon therapy for nonleft main true coronary bifurcations: The EBC drug-coated balloons (DCB) trial

Am Heart JPublished nonblinded, investigator-initiated, randomized control trial

Study context

Population
Patients with nonleft main true coronary bifurcations requiring revascularization, with significant atheroma in both main vessel and side branch; subacute (NSTEMI and unstable angina) and elective presentationsplanned recruitment
Participants
750 patients
Planned comparison
DCB vs drug-eluting stents (DES) in the treatment of coronary artery bifurcation disease
Primary endpoint
Target Bifurcation Failure (composite of cardiovascular death, target bifurcation myocardial infarction, or target bifurcation revascularization)
Follow-up
1 year
Methodological detailsopen-label, multicenter, international
  • Open-label
  • Multicenter
  • International

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

The European bifurcation club randomized trial of stepwise provisional stenting vs drug-coated balloon therapy for nonleft main true coronary bifurcations: The EBC DCB trial. Am Heart J. Published 29 April 2026. doi:10.1016/j.ahj.2026.107463

Summarised from the published abstract; every number is checked against it

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