Coronary disease & ACSRandomised controlled trial
Drug-Coated Balloon Angioplasty of the Side Branch During Provisional Stenting
- Randomised controlled trial
- multicentre
- 22 centres in China, Indonesia, Italy and Korea
Authors' conclusion
In patients with simple and true coronary bifurcation lesions undergoing provisional stenting, main vessel stenting with a DCB for the compromised side branch resulted in a lower 1-year rate of the composite outcome compared with an NCB intervention for the side branch.
Study context
- Population
- Patients with simple, true coronary bifurcations and side branch diameter stenosis ≥70% after main vessel stenting1-year follow-up completed in all
- Participants
- 784 patients
- Comparison
- Drug-coated balloons (DCB) vs noncompliant balloon (NCB) for the compromised side branch during provisional stenting
- DCBn = 391
- NCBn = 393reference
- Primary endpoint
- MACE:
- Cardiac death
- Target vessel MI
- Clinically driven target-lesion revascularization
- Follow-up
- 1 year
Primary result
As reported in the abstract
Hazard ratio
0.56
95% CI 0.35–0.88
P = 0.013
Events by treatment group
DCB vs NCB
HR 0.56 (95% CI 0.35–0.88); P = 0.013
Further findings
Procedural success, crossover to 2-stent approach, all-cause death, revascularization, stent thrombosis
- No significant differences between groups
Original publication
Drug-Coated Balloon Angioplasty of the Side Branch During Provisional Stenting. J Am Coll Cardiol. Published 28 October 2024. doi:10.1016/j.jacc.2024.08.067
Summarised from the published abstract; every number is checked against it