Cross-sectional study

Echocardiographic Reference Ranges of Global Longitudinal Strain for All Cardiac Chambers Using Guideline-Directed Dedicated Views

JACC Cardiovasc ImagingPublished

  • Cross-sectional study
  • population-based
  • HUNT4Echo substudy

Authors' conclusion

Reference ranges of strain for all cardiac chambers were established based on guideline-directed chamber-specific recordings. Age and sex were the most important factors influencing reference ranges

Study context

Population
Healthy participants from HUNT4Echo, the echocardiographic substudy of the 4th wave of the Trøndelag Health Studyhealthy
Participants
1,329 participants
Outcome
Reference ranges (incl. lower normal limits) of global strain for all 4 cardiac chambers by guideline-directed dedicated views

Main finding

As reported in the abstract

Strain reference ranges

Left ventricular (LV) global longitudinal strain

−24% to −16%

RV free-wall strain

−35% to −17%

Left atrial (LA) reservoir strain

17% to 49%

Right atrial (RA) reservoir strain

17% to 59%

Observational data: associations, not effects.

Further findings

Strain feasibility

LV
96%
RV
83%
LA
94%
RA
87%

Influence of subject characteristics

All strains lower absolute values with higher age, except LA and RA contractile strains, which were higher
All chamber-specific strains associated with age; LV strain associated with sex

Original publication

Echocardiographic Reference Ranges of Global Longitudinal Strain for All Cardiac Chambers Using Guideline-Directed Dedicated Views. JACC Cardiovasc Imaging. Published 1 November 2023. doi:10.1016/j.jcmg.2023.08.011

Summarised from the published abstract; every number is checked against it