Arrhythmias & electrophysiology
Voltage-guided pulmonary vein isolation for atrial fibrillation
Primary resultResult — go to the resultHazard ratio 1.00 95% CI 0.80–1.25Authors' conclusion
Voltage-guided PVI was noninferior to conventional LSI-guided PVI with respect to efficacy in the treatment of patients with AF, and its use significantly reduced procedure time.
Study context
- Population
- Patients with nonvalvular atrial fibrillation (AF) undergoing radiofrequency ablation
- Participants
- 370 patients
- Comparison
- Voltage-guided pulmonary vein isolation (PVI) vs conventional lesion size index (LSI)-guided PVI
- Voltagen = 189
- Controln = 181reference
- Primary endpoint
- AF recurrence, atrial flutter and atrial tachycardia (non-inferiority margin HR 1.4)
- Follow-up
- 1 year
Methodological detailsmulticentre, non-inferiority
- Multicentre
- Non-inferiority
Primary result
As reported in the abstract
Hazard ratio
1.00
95% CI 0.80–1.25
Events by treatment group
Voltagevs Control
HR 1.00 (95% CI 0.80–1.25)
Further findings
PVI time · significantly shorter with voltage
P < 0.001
Safety
Composite of procedure-related complications (primary safety end point)
P = 0.2791
Original publication
Voltage-guided pulmonary vein isolation for atrial fibrillation. Heart Rhythm. Published 22 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →