Heart failure & cardiomyopathies
Long Term Changes in Health-Related Quality of Life for People with Heart Failure: The Echocardiographic Heart of England Screening (ECHOES) Study
Authors' conclusion
People with a new diagnosis of HF at rescreening had a significant reduction in HRQoL. Conversely, for those with HF detected on initial screening, little change was observed in HRQoL scores on rescreening.
Study context
- Population
- ECHOES screening study and ECHOES-X follow-up participants
- Participants
- 1,618 participants
- Exposure
- New HF with reduced ejection fraction (HFrEF) or HF with preserved ejection fraction (HFpEF) at rescreening vs no heart failure (HF)
- Outcome
- Change in HRQoL (SF-36 version 1)
- Follow-up
- 13-year period
Methodological detailsmixed modelling, adjusted
- Mixed modelling
- Adjusted
Main finding
As reported in the abstract
Change in SF-36 physical functioning (PF) and role physical (RP) scores
Each group vs no HFAdjusted mean difference (95% CI)
HFrEFphysical functioning
−16.1(−22.2 to −10.1)
HFpEFphysical functioning
−14.6(−21.2 to −8.1)
HFrEFrole physical
−20.7(−31.8 to −9.7)
HFpEFrole physical
−19.3(−31.0 to −7.6)
Observational data: associations, not effects.
Further findings
Health-related quality of life (HRQoL) change, HF at baseline and rescreen
- Changes similar to no HF (except role emotion), from a much lower baseline score
Original publication
Long Term Changes in Health-Related Quality of Life for People with Heart Failure: The ECHOES Study. ESC Heart Fail. Published 2 October 2022. doi:10.
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