Heart failure & cardiomyopathiesResearch article
Improving Heart Failure Quality of Care Over the First Twenty Years: The Get With The Guidelines-Heart Failure Program
- national quality improvement initiative
- fully participating hospitals
- multivariable regression analysis, adjusting for patient and hospital characteristics
Authors' conclusion
The Get With The Guidelines-Heart Failure program was associated with sustained improvements in key achievement and quality measures for patients hospitalized with heart failure during its initial 2 decades, with a notable rise in the prescription of guideline-directed medical therapies and rapid implementation of new medications.
Study context
- Population
- Patients hospitalized with heart failure among Get With The Guidelines-Heart Failure fully participating hospitals between 2005 and 2024patient records, 819 participating hospitals
- Participants
- 1,561,093 patients
- Comparison
- Temporal changes in individual measures and outcomes between 2005 and 2024
Main finding
All-or-none composite achievement metric · between 2005 and 2024
Adjusted odds ratio
3.7
95% CI 3.5–4.0
P < 0.001
As reported in the abstract
Further findings
| Outcome | adjusted odds ratio (95% CI) | P value | |
|---|---|---|---|
| Mineralocorticoid receptor antagonist prescriptions among eligible patients | 22.3 (20.2–24.6) | P < 0.001 | |
| 0.050.21520Adjusted odds ratio (log scale) |
Mineralocorticoid receptor antagonist prescriptions among eligible patients
- Increase from 27.4% to 80.9%
Prescriptions of angiotensin receptor-neprilysin inhibitors and sodium-glucose cotransporter-2 inhibitors · 2024
- Angiotensin receptor-neprilysin inhibitors
- 67.3%
- Sodium-glucose cotransporter-2 inhibitors
- 78.2%
Other achievement and quality measures, including postdischarge follow-up and anticoagulation for atrial fibrillation or atrial flutter
- Sustained improvements
Equity of care by social vulnerability index
- Improved over time for evidence-based β-blockers and mineralocorticoid receptor antagonists
Vaccination rates and use of implantable cardioverter defibrillators
- Recent decreases
Patient characteristics
- median age
- 73 [62-83]
- women
- 47.4%
- median ejection fraction
- 45% [28%-58%]
Original publication
Summarised from the published abstract; every number is checked against it