Arrhythmias & electrophysiology
Education of healthcare professionals to improve guideline adherence in atrial fibrillation: the STEEER-AF cluster-randomized clinical trial
Authors' conclusion
Thus, while the education of healthcare professionals improved substantial gaps in implementation for rhythm control, it had no significant effect on stroke prevention.
Study context
- Population
- Patients with atrial fibrillation (AF) seen in routine practice
- Participants
- 1,732 patients70 centres
- Comparison
- Education of healthcare professionals vs standard practice
- Primary endpoint
- Co-primary: guideline adherence (ESC class I and III recommendations) on stroke prevention and on rhythm control
- Follow-up
- 6-9-months follow-up
Methodological details70 centres in six countries
- 70 centres in six countries
Primary result
As reported in the abstract
Guideline adherence
Intervention
- Stroke prevention
- 67.5%
- Rhythm control
- 33.9%
Control
- Stroke prevention
- 60.9%
- Rhythm control
- 22.9%
Stroke prevention
Intervention67.5%
Control60.9%
Rhythm control
Intervention33.9%
Control22.9%
Intervention vs ControlAdjusted relative risk (95% CI)P value
Stroke prevention
1.10(0.97–1.24)
P = 0.13Rhythm control
1.51(1.04–2.18)
P = 0.03Secondary outcomes
| Outcome | Improvement (%) (95% CI) | P value |
|---|---|---|
| Patient-reported integrated AF management | 5.1 (1.4%–8.9%) | P = 0.01 |
Original publication
Education of healthcare professionals to improve guideline adherence in atrial fibrillation: the STEEER-AF cluster-randomized clinical trial. Nat Med. Published 13 June 2025. doi:10. 1038/ s41591-025-03751-2
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