Arrhythmias & electrophysiology
Pulsed field ablation with a pentaspline catheter for ventricular arrhythmias: First US series
Authors' conclusion
In this first US series, VT/PVC ablation using a pentaspline PFA catheter for large VT substrate modification or after acute RFA failure appeared effective and safe, with promising acute and mid-term follow-up results.
Study context
- Population
- Consecutive patients undergoing pentaspline pulsed field ablation (PFA) for ventricular tachycardia (VT) or premature ventricular contractions (PVCs), May–October 2024 (VT substrate ablation in large scars or bailout after acute radiofrequency failure)9 VT, 2 PVC
- Participants
- 11 patients
- Outcome
- Safety and efficacy of pentaspline PFA for ventricular arrhythmias
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Bailout after acute radiofrequency ablation (RFA) failure: targeted VT/PVC suppressed in all cases
4
Large VT substrate modification or PVC: PFA only
2
Large VT substrate modification or PVC: touch-up RFA to complete substrate modification
5
Observational data: associations, not effects.
Further findings
Recurrence · mean follow-up 6 months
- VT recurrence (patients)
- 2
- PVC recurrence (patients)
- 1
Safety
Procedure-related complications
- No procedural-related complications
Original publication
Pulsed field ablation with a pentaspline catheter for ventricular arrhythmias: First US series. Heart Rhythm. Published 13 June 2025. doi:10. 1016/ j. hrthm. 2025. 06. 006
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