Aortic & peripheral vascular disease
Effect of a home-based calf neuromuscular electrical stimulation programme on walking capacity in adults with lower-extremity peripheral artery disease: the ELECTRO-PAD RCT
Primary result · Treadmill MWDResult — go to the resultBetween-group difference 69.9 m 95% CI 10.8–129.0Authors' conclusion
In patients with PAD and walking impairment, a 3-month home-based calf NMES program significantly improved walking capacity.
Study context
- Population
- Adults with lower-extremity peripheral artery disease (PAD) and walking impairment64 (88%) completed 3-month follow-up
- Participants
- 73 adults
- Comparison
- Home-based calf neuromuscular electrical stimulation (NMES) vs usual care
- NMESn = 34
- Usual caren = 39reference
- Primary endpoint
- Change in treadmill maximal walking distance (MWD)
- Follow-up
- 3 months
Methodological detailsmulticentre, 5 French university hospitals, September 2019 to July 2022; final follow-up November 2022
- Multicentre
- 5 French university hospitals
- September 2019 to July 2022; final follow-up November 2022
Primary result
Treadmill MWD
Between-group difference
69.9 m
95% CI 10.8–129.0
P = 0.02
By group
NMES
- Baseline
- 148.5 m
- 3 months
- 254.1 m
Usual care
- Baseline
- 142.5 m
- 3 months
- 175.8 m
Baseline
NMES148.5 m
Usual care142.5 m
3 months
NMES254.1 m
Usual care175.8 m
NMES vs Usual care
between-group difference 69.9 m (95% CI 10.8–129.0); P = 0.02
As reported in the abstract
Secondary outcomes
M
| Outcome | NMES | Usual care | Between-group difference (m) (95% CI) | P value | |
|---|---|---|---|---|---|
| 6-minute total walking distance · 3 months | 29.6 (5.1–54.1) | P = 0.02 | |||
| Baseline | 371.0 | 342.5 | |||
| 3 months | 405.4 | 348.8 | |||
| −50050100Difference, m (linear scale) |
Original publication
Effect of a home-based calf neuromuscular electrical stimulation programme on walking capacity in adults with lower-extremity peripheral artery disease: the ELECTRO-PAD RCT. Eur J Prev Cardiol. Published 9 February 2026. doi:10.
Summarised from the published abstract; every number is checked against it