Arrhythmias & electrophysiology
Efficacy and safety of pulsed field ablation for accessory pathways: a pilot study
Authors' conclusion
Pulsed field ablation of APs was feasible, effective, and safe. Its efficiency was remarkable for its ultrarapid termination of AP conduction.
Study context
- Population
- Conscious patients with accessory pathways (7 left anterolateral, 2 left inferolateral, 1 right posteroseptal)
- Participants
- 10 patients
- Outcome
- Acute procedural success and safety of PFA
- Follow-up
- Acute and 6 months
Main finding
As reported in the abstract
Acute procedural success
Acute procedural success
100%
Success after an initial application
6
60%
Further findings
Procedural times
- Total ablation time (s), mean ± SD
- 6.3 ± 4.9
- Ablation sites, mean ± SD
- 4.7 ± 1.8
- Ablation time at targets (s)
- 3.1 ± 2.4
- Ablation time at bolus sites (s)
- 3.2 ± 2.9
- Bolus ablation sites
- 3.2 ± 2
- Skin-to-skin time (min), mean
- 59.3 ± 15.5
- Pulsed field ablation (PFA) catheter dwell time (min)
- 29.4 ± 7.8
Safety
Adverse events · short-term follow-up
- Transient sinus arrest during PFA due to parasympathetic overexcitation
- 1 patient
- Sinus rhythm restored in all patients without any significant adverse events
Original publication
Efficacy and safety of pulsed field ablation for accessory pathways: a pilot study. Europace. Published 27 May 2024. doi:10.
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