Acute cardiac care & resuscitation
Efficacy of supraglottic airway devices in chest compression synchronized ventilation during continuous resuscitation: a prospective randomized cross-over cadaver study
Primary result · Reaching target pCCSV corridorResult — go to the resultOdds ratio 1.87 95% CI 0.91–3.83Authors' conclusion
SGA were associated with a lower likelihood of reaching the target range of pCCSV, lower Vte, and higher Vleak. Regardless the airway device, CCSV-failure is possible emphasizing the need for vigilant respiratory monitoring.
Study context
- Population
- Adult Thiel-embalmed cadavers
- Participants
- 11 participants
- Comparison
- Tracheal intubation (TI) vs SGA
- Primary endpoint
- Achieving pCCSV = 40 ± 3 mbar
Methodological detailsprospective, cross-over
- Prospective
- Cross-over
Primary result
Reaching target pCCSV corridor
Odds ratio
1.87
95% CI 0.91–3.83
P = 0.0864
TI vs SGA
OR 1.87 (95% CI 0.91–3.83); P = 0.0864
As reported in the abstract
- Ventilated with all airway types
- 2 (18 %)
- Ventilated only with TI
- 3 (27 %)
- Not sufficiently ventilated with any device incl. TI
- 2 (18 %)
Secondary outcomes
| Outcome | Estimate | P value |
|---|---|---|
| pCCSV, Vte and Vleak, TI vs SGATI vs SGA · pCCSV | regression coefficient 2.99 mbar (95% CI 1.63–4.35) | P < 0.0001 |
| pCCSV, Vte and Vleak, TI vs SGATI vs SGA · Vte | regression coefficient 42.42 ml (95% CI 32.07–52.27) | P < 0.0001 |
| pCCSV, Vte and Vleak, TI vs SGATI vs SGA · Vleak | regression coefficient −55.03 % (95% CI −62.92-47.15) | P < 0.0001 |
| pCCSV among individual SGAAmbu®AuraGain™ vs I-GEL® | regression coefficient −2.58 mbar (95% CI −4.04--1.13) | P = 0.0006 |
| pCCSV among individual SGAAmbu®AuraGain™ vs LTS-D® | regression coefficient −1.73 mbar (95% CI −3.18--0.27) | P = 0.0204 |
| pCCSV among individual SGALTS-D® vs I-GEL® | regression coefficient −0.86 mbar (95% CI −2.30-0.59) | P = 0.2434 |
Original publication
Efficacy of supraglottic airway devices in chest compression synchronized ventilation during continuous resuscitation: a prospective randomized cross-over cadaver study. Resuscitation. Published 2 September 2025. doi:10.
Summarised from the published abstract; every number is checked against it