Acute cardiac care & resuscitation

Tracheal intubation vs. supraglottic airway devices during mechanical intra-arrest-ventilation with volume-controlled-ventilation in out-of-hospital cardiac arrest: a cohort study

ResuscitationPublished Retrospective cohort study

Main finding · VTset−VTeResult — go to the resultRegression coefficient −128.3 ml 95 % CI −252.3 ml; −4.3 ml

Authors' conclusion

In OHCA cases receiving mechanical intra-arrest-ventilation with VCV, TI was associated with higher delivered VTe, less deviation from VTset, and significantly lower VLeak compared to SGA.

Study context

Population
Adults with out-of-hospital cardiac arrest (OHCA) receiving intra-arrest ventilation with volume-controlled ventilation, Gütersloh district EMS, Germany, 01/2019–08/2023682 min ventilation
Participants
27 adults
Exposure
Tracheal intubation (TI) vs supraglottic airway (SGA) during mechanical intra-arrest ventilation with volume-controlled-ventilation (VCV)
  • TIn = 14
  • SGAn = 13reference
Outcome
Difference VTset−VTe (set minus measured expiratory tidal volume)
Methodological detailsregistry-linked, single EMS district
  • Registry-linked
  • Single EMS district

Main finding

VTset−VTe

Regression coefficient

−128.3 ml

95 % CI −252.3 ml; −4.3 ml

P = 0.0427

As reported in the abstract

Observational data: associations, not effects.

Further findings

Measured expiratory tidal volume (VTe)

Set tidal volume (VTset)

Leakage volume (VLeak)

regression coefficient (%) −32.3 (−46.1 %; −18.4 %) · P < 0.0001

Original publication

Tracheal intubation vs. supraglottic airway devices during mechanical intra-arrest-ventilation with volume-controlled-ventilation in out-of-hospital cardiac arrest: a cohort study. Resuscitation. Published 4 December 2025. doi:10.1016/j.resuscitation.2025.110918

Summarised from the published abstract; every number is checked against it

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