Arrhythmias & electrophysiology
Efficient Patient-Specific Simulations of Ventricular Tachycardia Based on Computed Tomography-Defined Wall Thickness Heterogeneity
Authors' conclusion
The proposed framework allows for personalized simulations in a matter of hours. In 6 of 9 patients, simulations show re-entrant patterns matching intracardiac recordings.
Study context
- Population
- Patients referred for post-infarction ventricular tachycardia (VT) ablation (age 65 ± 11 years, 9 male)25 electroanatomical maps
- Participants
- 10 patients
- Outcome
- In silico VT induction and match with clinically mapped VT circuits
Main finding
As reported in the abstract
- Simulation time per pacing site (median)
- 6 min
- In silico VT induced with S1-S2 or S1-S2-S3 schemes in clinically inducible patients
- 9 of 10 patients
- VTs simulated in total (per patient)
- 42 (4.2 ± 2)
- In silico VTs matching a clinically mapped VT circuit
- 6
- Clinically induced VTs with detailed maps
- 6 VTs in 9 patients
Original publication
Efficient Patient-Specific Simulations of Ventricular Tachycardia Based on Computed Tomography-Defined Wall Thickness Heterogeneity. JACC Clin Electrophysiol. Published 4 October 2023. doi:10.
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