Arrhythmias & electrophysiology

50-W vs 40-W During High-Power Short-Duration Ablation for Paroxysmal Atrial Fibrillation: A Multicenter Prospective Study

JACC Clin ElectrophysiolPublished Prospective cohort study

Authors' conclusion

There was no significant difference in freedom from all-atrial arrhythmias or procedural safety outcomes between 50-W and 40-W during HPSD ablation of paroxysmal AF. The use of 50-W was associated with a higher rate of first-pass PVI as well as shorter procedural times.

Study context

Population
Patients undergoing high-power short-duration (HPSD) radiofrequency ablation of paroxysmal AF in the REAL-AF registry
Participants
383 patients
Exposure
50-W vs 40-W during HPSD ablation
Outcome
Efficacy: freedom from all-atrial arrhythmias; safety: any procedural complication
Follow-up
12 months
Methodological detailsanalysis of the REAL-AF registry, multicentre
  • Analysis of the REAL-AF registry
  • Multicentre

Main finding

As reported in the abstract

Freedom from all-atrial arrhythmias

P = 0.387

Observational data: associations, not effects.

Secondary outcomes

First-pass PVI

P = 0.040

Procedural time

P < 0.001

Radiofrequency ablation time

P < 0.001

Safety

Any procedural complication (primary safety outcome) · 12 months

P = 0.646

Original publication

50-W vs 40-W During High-Power Short-Duration Ablation for Paroxysmal Atrial Fibrillation: A Multicenter Prospective Study. JACC Clin Electrophysiol. Published 4 October 2023. doi:10.1016/j.jacep.2023.08.005

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