Arrhythmias & electrophysiology
Electrical Heterogeneity in Hispanic Background Subpopulations: The HCHS/SOL
Authors' conclusion
In CVD-free Hispanic/Latino subpopulations, cardiovascular risk factors do not fully explain GEH differences across ethnic background categories, which likely reflect unmeasured health disparities.
Study context
- Population
- Hispanic/Latino adults in HCHS/SOL (mean age 41 years)
- Participants
- 15,684 adults
- Exposure
- Hispanic/Latino background subpopulations vs total mean
- Outcome
- Vectorcardiographic GEH (spatial QRS-T angle, SVG azimuth, SVG elevation, SVG magnitude, sum absolute QRST integral)
Main finding
As reported in the abstract
Adjusted GEH vs total mean
Each group vs total meanDifference, ° (95% CI)P value
Dominicanspatial QRS-T angle, narrower
−3.4(−5.0° to −1.7°)
P < 0.0001Each group vs total meanDifference (95% CI)
South AmericanSVG azimuth, more anterior
−2.9(−4.4 to −1.4)
MexicanSVG azimuth, more anterior
−3.5(−4.3 to −2.6)
Difference
- Dominican · spatial ventricular gradient (SVG) azimuth, more posterior
- +2.9 (95% CI 1.6–4.2)
- Puerto Rican · SVG azimuth, more posterior
- +3.8 (95% CI 2.4–5.2)
Observational data: associations, not effects.
Further findings
Association of CHD with Global Electrical Heterogeneity (GEH), by background
- Association especially strong in Cuban background subpopulation
Original publication
Electrical Heterogeneity in Hispanic Background Subpopulations: The HCHS/SOL. JACC Adv. Published 11 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →