Heart failure & cardiomyopathies
Electrical Storm in Patients With Hypertrophic Cardiomyopathy
Authors' conclusion
ES in HCM frequently resolves using antiarrhythmic drugs. Many patients will present with VA recurrences. Long-term outcomes were poor, and one-fourth of the patients ended up dying at 18 months.
Study context
- Population
- Patients with hypertrophic cardiomyopathy (HCM) experiencing electrical storm, 2017–2023
- Participants
- 23 patients
- Outcome
- Acute management, in-hospital mortality and long-term outcomes
Methodological detailsmulticentre, 6 tertiary centres
- Multicentre
- 6 tertiary centres
Main finding
As reported in the abstract
- Amiodarone
- n = 20 [87%]
- Beta-blockers
- n = 16 [70%]
- Radiofrequency catheter ablation
- 10 patients (44%)
- In-hospital VA recurrence
- 8 patients
- In-hospital death
- Two (9%)
- Death after discharge (median follow-up 18 months)
- 4
- Arrhythmia recurrence
- Seven patients (30%)
Observational data: associations, not effects.
Further findings
Baseline characteristics
- Mean age
- 61.5 ± 15.2 years
- Male
- 73.9%
- LVEF
- 50% ± 14%
- Apical aneurysm
- Five patients (22%)
- History of VA
- Ten (43.4%)
- Monomorphic VT
- 18 patients [78%]
Ablation and outcomes
- Negative programmed ventricular stimulation after ablation
- 4 patients
- In-hospital VA recurrence: previously ablated vs nonablated
- 2 [25%] vs 6 [75%]
- Arrhythmia recurrence after ablation
- 4
- Radiofrequency ablation not associated with better outcomes (recurrence rate or overall survival)
Original publication
Electrical Storm in Patients With Hypertrophic Cardiomyopathy. JACC Clin Electrophysiol. Published 20 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →