Heart failure & cardiomyopathies
Association between programmed electrical stimulation inducibility and arrhythmic risk in hypertrophic cardiomyopathy: a systematic review and meta-analysis
Pooled result · MAEResult — go to the resultOdds ratio 10.83 95% CI 3.52–33.34Authors' conclusion
PES inducibility is associated with a 10 times higher risk of MAE in patients with HCM.
Study context
- Population
- Patients with hypertrophic cardiomyopathy (HCM)
- Participants
- 587 patients5 studies
- Comparison
- Programmed electrical stimulation (PES) inducible vs non-inducible
- Induciblen = 188
- Outcome
- Major arrhythmic events (MAE) (sudden cardiac death (SCD), resuscitated cardiac arrest or appropriate ICD interventions)
Methodological detailsrandom-effects
- Random-effects
Pooled result
MAE
Odds ratio
10.83
95% CI 3.52–33.34
P < 0.001
Events by group
Induciblevs Non-inducible
OR 10.83 (95% CI 3.52–33.34); P < 0.001
As reported in the abstract
Further pooled results
| Outcome | Values |
|---|---|
| Predictive value of PES for MAE | PES Sensitivity 81% · Specificity 72% · PPV 18% · NPV 98% |
Original publication
Association between programmed electrical stimulation inducibility and arrhythmic risk in hypertrophic cardiomyopathy: a systematic review and meta-analysis. Heart. Published 16 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →