Arrhythmias & electrophysiology

Electrogram Morphology Recurrence for Mapping Persistent Atrial Fibrillation: Initial vs Redo Catheter Ablation

JACC Clin ElectrophysiolPublished Mechanistic study

Authors' conclusion

EMR identified the shortest CLR sites in the PVs in 59% of patients undergoing initial persistent AF ablation, consistent with reported success rates of ∼50% for PV isolation.

Study context

Population
Patients undergoing ablation for persistent atrial fibrillation (AF)30 males
Participants
42 patients
Comparison
First vs redo ablation for persistent AF
  • Group 1n = 32reference
  • Group 2n = 10
Outcome
EMR in LA and RA: most recurrent electrogram (EGM) morphology frequency (Rec%) and recurrence cycle length (CLR)
Methodological detailsmultisite left atria (LA)/right atria (RA) mapping
  • Multisite LA/RA mapping

Main finding

As reported in the abstract

Minimum CLR
  • Group 2 vs Group 1: P = 0.20
  • Group 1: P = 0.0005
  • Group 2 vs Group 1: P = 0.75
  • Groups 1 and 2 values reported in order in one sentence

Further findings

Shortest CLR in the LA

P = 0.04

OutcomeGroup 1Group 2P value
Shortest CLR in the PVsP = 0.01
Of3210

Sites with Rec% <50%

Most sites had Rec% <50%
77.6%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Electrogram Morphology Recurrence for Mapping Persistent Atrial Fibrillation: Initial vs Redo Catheter Ablation. JACC Clin Electrophysiol. Published 18 January 2023. doi:10.1016/j.jacep.2022.11.003

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