Arrhythmias & electrophysiology
Safety and Efficacy of a Novel Approach to Pulmonary Vein Isolation Using Prolonged Apneic Oxygenation
Authors' conclusion
A novel strategy of performing complete PVI during apneic oxygenation results in improved catheter stability and decreased ablation times without adverse events.
Study context
- Population
- Patients with paroxysmal AF undergoing pulmonary vein isolation (PVI) (mean age 63 ± 11 years; 37% women)
- Participants
- 128 patients
- Exposure
- PVI under apneic oxygenation vs standard ventilation
- Apnean = 64
- Controln = 64reference
- Outcome
- Safety and efficacy of PVI during prolonged apneic oxygenation (catheter stability)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Mean catheter displacement
P < 0.001
Observational data: associations, not effects.
Further findings
Contact force SD
P = 0.046
Lesions with mean catheter displacement >2 mm
P < 0.001
Total ablation time to achieve PVI
P = 0.001
First-pass PVI, acute and dormant PV reconnections
- Similar rates between the two groups
Safety
- No adverse events with apneic oxygenation strategy
Original publication
Safety and Efficacy of a Novel Approach to Pulmonary Vein Isolation Using Prolonged Apneic Oxygenation. JACC Clin Electrophysiol. Published 18 January 2023. doi:10.
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