Heart failure & cardiomyopathies
Electronic Nudges to Increase Influenza Vaccination Uptake Among Patients with Heart Failure: A Pre-Specified Analysis of the NUDGE-FLU Trial
Authors' conclusion
HF status did not modify the effectiveness of cardiovascular gain-framed and repeated electronic nudging letters in increasing influenza vaccination rates.
Study context
- Population
- Danish citizens ≥65 years with heart failure (HF) at baseline (NUDGE-FLU); overall Danish HF population incl. <65 yearswith HF at baseline
- Participants
- 33,109 participants
- Comparison
- Electronic nudging letters vs usual care in patients with HF
- Primary endpoint
- Receipt of an influenza vaccine
Methodological detailspre-specified analysis, nationwide
- Pre-specified analysis
- Nationwide
Primary result
As reported in the abstract
Effect modification of nudges on vaccination by HF status
- HF status did not modify effect of cardiovascular gain-framed letter
- pinteraction = 0.37
- HF status did not modify effect of repeated letter
- pinteraction = 0.55
Further findings
Vaccination uptake by baseline GDMT level
P < 0.001
Influenza vaccination uptake, overall Danish HF population (2022-2023 season)
- Uptake, overall HF population (n = 65 075)
- 71.6%
- Uptake, <65 years
- 44.6%
Effect modification by guideline-directed medical therapy (GDMT) use level
- No effect modification for repeated letter
- P for interaction = 0.88
- Trend towards attenuated effect of cardiovascular gain-framed letter with low GDMT
- P for interaction = 0.07
Longitudinal GDMT use
- Letters had no impact on longitudinal GDMT use
Original publication
Electronic Nudges to Increase Influenza Vaccination Uptake Among Patients with Heart Failure: A Pre-Specified Analysis of the NUDGE-FLU Trial. Eur J Heart Fail. Published 4 June 2023. doi:10.
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