Prevention & lipids

Enhancing the Cardiovascular Health Construct With a Psychological Health Metric for Predicting Mortality Risk

JACC AdvPublished Prospective cohort study

Authors' conclusion

A CVH construct enhanced with psychological health strongly predicts mortality.

Study context

Population
US adults (mean age 48y, 51% female), NHANES 2011–2018
Participants
21,183 adults
Exposure
High vs low cardiovascular health (CVH) score
Outcome
All-cause mortality
Methodological detailsnationally representative survey (NHANES 2011–2018)
  • Nationally representative survey (NHANES 2011–2018)

Main finding

As reported in the abstract

All-cause mortality, high vs low CVH score
High vs low CVH score enhanced with PHQ-2: lower mortality risk
69%
High vs low CVH score enhanced with PHQ-9: lower mortality risk
70%
High vs low LE8 score: lower mortality risk
65%
Trend across CVH categories
p-trend<0.001

Observational data: associations, not effects.

Further findings

Mortality by sex and race and ethnicity (subgroups)

Higher LE8 and enhanced CVH scores predicted lower mortality in both sexes and in Black and White but not Hispanic adults

CV and cancer mortality

CV deaths
414
Cancer deaths
329
Higher LE8 and enhanced CVH scores associated with lower CV and cancer mortality

Mortality prediction (C-statistic)

Enhanced CVH scores vs LE8 score, C-statistic
0.843 vs 0.842
P
P < 0.001

Original publication

Enhancing the Cardiovascular Health Construct With a Psychological Health Metric for Predicting Mortality Risk. JACC Adv. Published 26 July 2024. doi:10.1016/j.jacadv.2024.101112

Composed by AI from the published abstract and checked against it. How Briefs are made →

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