Arrhythmias & electrophysiology

Epicardial and hybrid surgical ablation of atrial fibrillation: 1-year follow-up outcomes of the EORP epicardial and hybrid atrial fibrillation ablation (EHAFA) registry

EuropacePublished Prospective observational registry

Authors' conclusion

This international registry revealed good rhythm control efficacy for epicardial and hybrid AF ablation in patients with advanced AF, leading to improvement in AF-related symptoms. However, a certain associated complication rate needs to be considered.

Study context

Population
Patients undergoing stand-alone minimally invasive epicardial or hybrid ablation for all types of atrial fibrillation (AF), 17 centres in 10 countries, 2016–2018
Participants
468 patients17 centres10 countries
Exposure
Epicardial vs Hybrid
  • Epicardialn = 220
  • Hybridn = 244
Outcome
Freedom from atrial arrhythmias >30 s with and without antiarrhythmic drugs
Follow-up
1 year
Methodological detailsinternational, multicentre, consecutive enrolment
  • International
  • Multicentre
  • Consecutive enrolment

Main finding

As reported in the abstract

Freedom from atrial arrhythmias >30 s

With antiarrhythmic drug usage (n = 279/353)

79%

Without antiarrhythmic drug usage (n = 223/351)

64%

Observational data: associations, not effects.

Further findings

EHRA class I · follow-up vs preoperative

At follow-up (n = 233/325)
72%
Preoperatively (n = 14/464)
3%

Safety

In-hospital major complications

Overall major complication rate (n = 38/464)
8.2%

Original publication

Epicardial and hybrid surgical ablation of atrial fibrillation: 1-year follow-up outcomes of the EORP EHAFA registry. Europace. Published 19 September 2025. doi:10.1093/europace/euaf196

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