Arrhythmias & electrophysiology

Essential antiarrhythmic drug accessibility worldwide: a multi-survey study and comprehensive evaluation of access and supply challenges

EuropacePublished Cross-sectional survey study

Authors' conclusion

Physicians worldwide frequently encounter problems accessing guideline-recommended antiarrhythmic drugs for their patients, which putatively impacts their patients' quality of life and life expectancy.

Study context

Population
Members of EHRA, AEPC, ERN GUARD-Heart and national heart rhythm societies
Participants
558 members · 80 countries
Outcome
Current access to AADs (proportion of surveyed AADs considered readily accessible)
Methodological detailsmulti-survey, online surveys, international
  • Multi-survey
  • Online surveys
  • International

Main finding

As reported in the abstract

Readily accessible AADs (main analysis: ≥5 respondents; 16 EU, 7 non-EU countries)

Surveyed AADs considered readily accessible

16-59%

Oral flecainide and propranolol available in countries

88%

Mexiletine solution available in countries

10%

Observational data: associations, not effects.

Further findings

National societies' perception of impact

Limited access negatively affected patients' quality of life
72%
Limited access negatively affected life expectancy
35%
Expected challenges to persist or worsen
73%

Original publication

Essential antiarrhythmic drug accessibility worldwide: a multi-survey study and comprehensive evaluation of access and supply challenges. Europace. Published 2 September 2026. doi:10.1093/europace/euag220

Summarised from the published abstract; every number is checked against it

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