Arrhythmias & electrophysiology
Estimated sodium intake and premature ventricular complexes: data from the population-based Swedish CArdioPulmonary bioImage Study
Authors' conclusion
There was a U-shaped association between sodium intake and PVC frequency, with both low and high sodium intake associated with higher PVC frequency.
Study context
- Population
- Individuals in the randomly selected population-based Swedish CArdioPulmonary bioImage Study cohort with 24-hour ECG registration and fasting morning urine samplingindividuals with 24-hour ECG registration and fasting morning urine sampling
- Participants
- 5,636 individuals
- Exposure
- Strata of estimated sodium intake (Kawasaki formula) vs the reference of 3-3.99 g/day, for PVC frequency
- Outcome
- PVC frequency by estimated sodium intake
Methodological detailspopulation-based, randomly selected
- Population-based
- Randomly selected
Main finding
As reported in the abstract
Increase in PVC frequency (95% CI)P value
<2 g/dayvs 3-3.99 g/daymultivariable negative binomial regression
26%(6%–49%)
≥5 g/dayvs 3-3.99 g/daymultivariable negative binomial regression
52%(26%–84%)
P < 0.012-2.99 g/dayvs 3-3.99 g/daynot associated
5%(−8% to 20%)
4-4.99 g/dayvs 3-3.99 g/daynot associated
4%(−11% to 22%)
Observational data: associations, not effects.
Further findings
Participant characteristics
- Median age
- 57.6 years
- Female
- 51.9%
- Median daily PVC count
- 8 (IQR 3-41)
- ≥500 premature ventricular complexes (PVCs)/24 hours
- 5.9%
- Mean estimated sodium intake
- 3.3 g/day
Original publication
Estimated sodium intake and premature ventricular complexes: data from the population-based Swedish CArdioPulmonary bioImage Study. Heart. Published 17 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →