Arrhythmias & electrophysiology

Ethnic Differences in Atrial Fibrillation in the United Kingdom

JACC AdvPublished Prospective cohort study

Authors' conclusion

In a European population with universal access to health care, White individuals consistently experienced the highest risk of AF, but there were no detectable differences in AF-related stroke or systemic infarcts.

Study context

Population
UK Biobank participants, January 1, 2006 to June 30, 20208,706 incident atrial fibrillation (AF)
Participants
458,785 participants
Exposure
Black, South Asian, Chinese and multiracial vs White ethnicity
  • Whiten = 438,333reference
  • Blackn = 7,244
  • South Asiann = 9,143
  • Chinesen = 1,376
  • Multiracialn = 2,689
Outcome
Incident AF; AF-related stroke and systemic infarcts
Methodological detailsUK Biobank
  • UK Biobank

Main finding

As reported in the abstract

Incident AF
Multivariable adjusted
Each group vs whiteHazard ratio (95% CI)P value
Black
0.60(0.49–0.74)
P < 0.001
South Asian
0.59(0.49–0.72)
P < 0.001
Chinese
0.31(0.12–0.83)
P = 0.002

Observational data: associations, not effects.

Further findings

AF-related stroke and systemic infarct (in AF participants)

Incident stroke and systemic infarct in AF participants
1,550
No significant differences by ethnicity
  • Small numbers of events

Original publication

Ethnic Differences in Atrial Fibrillation in the United Kingdom. JACC Adv. Published 3 July 2024. doi:10.1016/j.jacadv.2024.101043

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