Aortic & peripheral vascular diseaseCohort study
Evaluation of CT-FFR for predicting myocardial ischaemia in patients with type A aortic dissection
- retrospective study
- consecutive
Authors' conclusion
CT-FFR is significantly associated with post-operative MACE in TAAD patients. As a non-invasive functional assessment tool, CT-FFR may help identify high-risk patients and optimize post-operative management strategies.
Study context
- Population
- TAAD patients who underwent coronary computed tomography angiography (CCTA) between January 2023 and February 2024140 underwent surgery · underwent surgery 140
- Participants
- 154 patients
- Exposure
- CT-FFR ≤0.80 and 30-day post-operative MACE; incremental predictive value of CT-FFR beyond CCTA and clinical risk factors
- Outcome
- 30-day post-operative MACE in surgically treated patients:
- All-cause death
- Non-fatal myocardial infarction
- Unplanned revascularization
- Follow-up
- 30-day post-operative
Main finding
As reported in the abstract
Adjusted odds ratio
7.18
95% CI 2.86–18.07
P < 0.001
CT-FFR ≤0.80
adjusted odds ratio 7.18 (95% CI 2.86–18.07); P < 0.001
- of the 140 who underwent surgery, experienced 30-day post-operative MACE
- 34 (24.3%)
Observational data: associations, not effects.
Further findings
Discrimination for 30-day post-operative MACE, model combining CT-FFR with CCTA findings and clinical risk factors
- area under the curve
- 0.783
- high sensitivity and a high negative predictive value
Original publication
Evaluation of CT-FFR for predicting myocardial ischaemia in patients with type A aortic dissection. Eur Heart J Cardiovasc Imaging. Published 27 February 2026. doi:10.1093/ehjci/jeag052
Summarised from the published abstract; every number is checked against it