Evolving use and clinical outcomes of coronary intravascular lithotripsy: insights from an international, multicentre registry
Authors' conclusion
In this real-world registry, IVL demonstrated efficacy across diverse clinical and anatomical settings. High success rates, low complication rates and MACE rates were observed acutely and at 1-year follow-up.
Study context
- Population
- Unselected real-world patients undergoing coronary intravascular lithotripsy (IVL) for coronary artery calcification, May 2019 to February 2024
- Participants
- 454 patients
- Outcome
- Key endpoints: device, technical and procedural success, IVL-related complications and MACE
- Follow-up
- 1-year follow-up
Methodological detailsinternational, 7 centres in 2 European countries
- International
- 7 centres in 2 European countries
Main finding
As reported in the abstract
Device, technical and procedural success
Device success
98%
Technical success
91%
Procedural success
89%
Observational data: associations, not effects.
Further findings
Utilisation trends over time
- Increased IVL use in ACS
- P = 0.004
- Increased IVL use with intracoronary imaging
- P = 0.002
- Decreased use of other calcium modification devices
- P = 0.034
Safety
IVL-related complications
- IVL-related complications, 6 patients
- 1%
Major adverse cardiovascular events (MACE) · 1-year follow-up
- MACE, 37 patients
- 13%
Original publication
Evolving use and clinical outcomes of coronary intravascular lithotripsy: insights from an international, multicentre registry. Heart. Published 29 October 2024. doi:10.
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