Heart failure & cardiomyopathies
Exercise Training in Left Ventricular Assist Device Patients: Protocol of an Individual Participant Data Meta-Analysis
Authors' conclusion
Our study will be the first to harmonize IPD in meta-analysis to demonstrate the effects of exercise training on exercise performance and QoL over standard care in LVAD patients.
Study context
- Population
- Patients with left ventricular assist device (LVAD)
- Comparison
- Exercise training vs standard care
Methodological detailsrandom effects, one-stage and two-stage approaches, individual participant data (IPD) to be requested from corresponding authors of eligible RCTs, checked, recalculated, merged and screened for quality, risk of bias and heterogeneity
- Random effects
- One-stage and two-stage approaches
- IPD to be requested from corresponding authors of eligible RCTs, checked, recalculated, merged and screened for quality, risk of bias and heterogeneity
Pooled result
As reported in the abstract
- Expected: superior effects of exercise training on submaximal exercise capacity and quality of life (QoL), similar effects on maximal aerobic capacity vs standard care
- Protocol; no results reported
Original publication
Exercise Training in Left Ventricular Assist Device Patients: Protocol of an Individual Participant Data Meta-Analysis. ESC Heart Fail. Published 25 September 2024. doi:10. 1002/ ehf2. 15063
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