Coronary disease & ACS

Exercise type and settings, quality of life, and mental health in coronary artery disease: a network meta-analysis

Eur Heart JPublished Systematic review and network meta-analysis of randomised trials

Authors' conclusion

Exercise training, especially in-person sessions, was associated with improved HR-QoL, depression and anxiety, independently of exercise type.

Study context

Population
Patients with CAD42 RCTs, 36 meta-analysed
Comparison
Exercise types and settings vs no exercise
Outcome
HR-QoL, depression and anxiety (meta-analysed outcomes)
Methodological detailsparallel group design
  • Parallel group design

Pooled result

As reported in the abstract

HR-QoL
Each group vs no exerciseSMD (95% CI)
HIIT + R
1.53(0.83–2.24)
HIIT
0.44(0.15–0.73)
MIT
0.44(0.20–0.67)

Further pooled results

OutcomeSMD (95% CI)
Exercise setting: HR-QoL, depressive and anxiety symptomsIn-personvs No exerciseHR-QoL0.51 (0.28–0.74)
Exercise setting: HR-QoL, depressive and anxiety symptomsIn-personvs No exerciseDepressive symptoms−0.55 (−1.03 to −0.07)
Exercise setting: HR-QoL, depressive and anxiety symptomsIn-personvs No exerciseAnxiety symptoms−1.16 (−2.05 to −0.26)

Exercise setting: Health-related quality of life (HR-QoL), depressive and anxiety symptoms

Home-based programmes not significantly associated with improvements in these outcomes

Secondary (intervention duration and volume) and sensitivity analyses excluding high risk of bias studies

Findings robust

Original publication

Exercise type and settings, quality of life, and mental health in coronary artery disease: a network meta-analysis. Eur Heart J. Published 15 January 2025. doi:10.1093/eurheartj/ehae870

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