Acute cardiac care & resuscitation
Expedited conveyance of out-of-hospital-cardiac arrest patients with STEMI and shockable rhythms to Cardiac Arrest Centres − A feasibility pilot study of the British Cardiovascular Intervention Society conveyance algorithm
Main finding · Death from any causeResult — go to the resultRelative risk 1.10 95% CI 0.98–1.24Authors' conclusion
The BCIS algorithm is feasible and did not impact overall mortality, but there is signal that direct conveyance of OHCA patients with an initial shockable rhythm and low MIRACLE2 score, to a dedicated CAC may improve survival.
Study context
- Population
- Patients with out-of-hospital cardiac arrest (OHCA) from suspected cardiac aetiology from the county of Essex, United Kingdom, April 2022-April 2023mean age 67.5 ± 13.1, 66% male
- Participants
- 330 patients
- Exposure
- BCIS conveyance algorithm vs conveyance as standard of care
- Standard care groupn = 162
- BCIS conveyance groupn = 168reference
- Outcome
- death from any cause
- Follow-up
- 30 days
Methodological detailsfeasibility pilot, consecutive patients, before-and-after (first 6 months standard of care, next 6 months BCIS protocol)
- Feasibility pilot
- Consecutive patients
- Before-and-after (first 6 months standard of care, next 6 months BCIS protocol)
Main finding
As reported in the abstract
Relative risk
1.10
95% CI 0.98–1.24
P = 0.10
By group
Standard care groupvs BCIS conveyance group
RR 1.10 (95% CI 0.98–1.24); P = 0.10
Observational data: associations, not effects.
Secondary outcomes
30-day survival with favourable neurological outcome (secondary outcome)
| Standard care group | BCIS conveyance group | RR (CI) | P value | ||
|---|---|---|---|---|---|
| 30-day survival with favourable neurological outcomeDirection not stated in the abstract · numerically higher with algorithm implementation | 15% | 19% | 1.05 (0.95–1.15) | P = 0.38 | |
| 0.512Relative risk (log scale) |
| Outcome | Standard care group | BCIS conveyance group | RR (95% CI) | P value | |
|---|---|---|---|---|---|
| 30 day mortality in those with an initial shockable rhythm (post hoc) · lower mortality with BCIS conveyance algorithm · Post hoc analysis | 61% | 41% | 1.5 (1.05–2.13) | P = 0.02 | |
| 0.512Relative risk (log scale) |
| Outcome | Standard care group | BCIS conveyance group | RR (95% CI) | P value |
|---|---|---|---|---|
| 30 day mortality in those with a MIRACLE2 score ≤ 5 (post hoc) · direction not stated in the abstract · Post hoc analysis | 63%% | 38% | 0.59 (0.61–0.86) | P = 0.005 |
Original publication
Expedited conveyance of out-of-hospital-cardiac arrest patients with STEMI and shockable rhythms to Cardiac Arrest Centres − A feasibility pilot study of the British Cardiovascular Intervention Society conveyance algorithm. Resuscitation. Published 4 January 2025. doi:10. 1016/ j. resuscitation. 2025. 110491
Composed by AI from the published abstract and checked against it. How Briefs are made →