Acute cardiac care & resuscitation

Expedited conveyance of out-of-hospital-cardiac arrest patients with STEMI and shockable rhythms to Cardiac Arrest Centres − A feasibility pilot study of the British Cardiovascular Intervention Society conveyance algorithm

ResuscitationPublished observational pilot study

Main finding · Death from any causeResult — go to the resultRelative risk 1.10 95% CI 0.98–1.24

Authors' conclusion

The BCIS algorithm is feasible and did not impact overall mortality, but there is signal that direct conveyance of OHCA patients with an initial shockable rhythm and low MIRACLE2 score, to a dedicated CAC may improve survival.

Study context

Population
Patients with out-of-hospital cardiac arrest (OHCA) from suspected cardiac aetiology from the county of Essex, United Kingdom, April 2022-April 2023mean age 67.5 ± 13.1, 66% male
Participants
330 patients
Exposure
BCIS conveyance algorithm vs conveyance as standard of care
  • Standard care groupn = 162
  • BCIS conveyance groupn = 168reference
Outcome
death from any cause
Follow-up
30 days
Methodological detailsfeasibility pilot, consecutive patients, before-and-after (first 6 months standard of care, next 6 months BCIS protocol)
  • Feasibility pilot
  • Consecutive patients
  • Before-and-after (first 6 months standard of care, next 6 months BCIS protocol)

Main finding

As reported in the abstract

Relative risk

1.10

95% CI 0.98–1.24

P = 0.10

By group

Standard care groupvs BCIS conveyance group
RR 1.10 (95% CI 0.98–1.24); P = 0.10

Observational data: associations, not effects.

Secondary outcomes

30-day survival with favourable neurological outcome (secondary outcome)

Standard care groupBCIS conveyance groupRR (CI)P value
30-day survival with favourable neurological outcomeDirection not stated in the abstract · numerically higher with algorithm implementation15%19%1.05 (0.95–1.15)P = 0.38
OutcomeStandard care groupBCIS conveyance groupRR (95% CI)P value
30 day mortality in those with an initial shockable rhythm (post hoc) · lower mortality with BCIS conveyance algorithm · Post hoc analysis61%41%1.5 (1.05–2.13)P = 0.02
OutcomeStandard care groupBCIS conveyance groupRR (95% CI)P value
30 day mortality in those with a MIRACLE2 score ≤ 5 (post hoc) · direction not stated in the abstract · Post hoc analysis63%%38%0.59 (0.61–0.86)P = 0.005

Original publication

Expedited conveyance of out-of-hospital-cardiac arrest patients with STEMI and shockable rhythms to Cardiac Arrest Centres − A feasibility pilot study of the British Cardiovascular Intervention Society conveyance algorithm. Resuscitation. Published 4 January 2025. doi:10.1016/j.resuscitation.2025.110491

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