Prevention & lipids

Exposure to ultra-processed food and risk of cardiovascular mortality: a prospective cohort study

Eur J Prev CardiolPublished Prospective cohort study

Main finding · CV mortalityResult — go to the resultHazard ratio 1.19 95% CI 1.09–1.29

Authors' conclusion

Aligning with findings from the USA and Europe, higher exposure to the ultra-processed food pattern was prospectively associated with a higher risk of cardiovascular mortality.

Study context

Population
Australian adults, Melbourne Collaborative Cohort Study (baseline 1990–94), mean age 55.1 years, 60% female4,229 CV deaths
Participants
39,544 adults
Exposure
Highest vs lowest quartile of energy-adjusted ultra-processed food exposure
Outcome
CV mortality
Follow-up
Median 25.1 years
Methodological detailsFine and Gray competing risk models
  • Fine and Gray competing risk models

Main finding

As reported in the abstract

Hazard ratio

1.19

95% CI 1.09–1.29

P < 0.001 for trend

Quartile 4vs Quartile 1
HR 1.19 (95% CI 1.09–1.29); P for trend < 0.001

Observational data: associations, not effects.

Original publication

Exposure to ultra-processed food and risk of cardiovascular mortality: a prospective cohort study. Eur J Prev Cardiol. Published 25 June 2025. doi:10.1093/eurjpc/zwaf378

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