Feasibility and prognostic significance of ventricular–arterial coupling after myocardial infarction: the RIGID-MI cohort
Main finding · MACE by PWV/GLS ratio >0.70Result — go to the resultHazard ratio 2.2 95% CI 1.14–4.27Authors' conclusion
The PWV/GLS ratio, assessed 1 month after MI, identifies a group of patients at higher risk of MACE providing additional value on top of conventional non-invasive parameters.
Study context
- Population
- Stable patients with left ventricular ejection fraction (LVEF) ≥40% 1 month after myocardial infarction (MI)
- Participants
- 374 patients
- Outcome
- MACE:
- All-cause death
- Acute HF
- Stroke
- AMI
- Urgent CV hospitalization
- Follow-up
- Median 32 months (IQR 16-42)
Main finding
MACE by PWV/GLS ratio >0.70
Hazard ratio
2.2
95% CI 1.14–4.27
P = 0.02
PWV/GLS ratio >0.70
HR 2.2 (95% CI 1.14–4.27); P = 0.02
As reported in the abstract
- Major adverse cardiovascular events (MACE) occurred
- 41 (11%)
Observational data: associations, not effects.
Further findings
Feasibility of ventricular-arterial coupling (VAC) parameters
- Elastance (Ea)/Ees obtained at rest
- 354 (95%)
- Pulse wave velocity (PWV)/global longitudinal strain (GLS) obtained at rest
- 253 (68%)
- Isometric exercise workable
- 335 (85%)
Original publication
Feasibility and prognostic significance of ventricular–arterial coupling after myocardial infarction: the RIGID-MI cohort. Eur Heart J Cardiovasc Imaging. Published 22 December 2023. doi:10.
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