Coronary disease & ACS

Sex Differences in Coronary Artery Disease Characteristics Among Patients With Type 2 Myocardial Infarction

JACC AdvPublished Prospective cohort study

Authors' conclusion

Among patients with type 2 MI, prevalence of any CAD and obstructive CAD did not differ according to sex. Total plaque volume was similar between sexes, but women had a lower volume of low-attenuation plaque

Study context

Population
Patients with strictly adjudicated type 2 myocardial infarction (MI) evaluated with coronary CT angiography and fractional flow reserve50% women
Participants
50 patients
Exposure
Women vs men
Outcome
Sex-based differences in prevalence and nature of CAD
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Prevalence of any CAD, obstructive CAD and hemodynamically significant focal stenosis (women vs men)

Any coronary artery disease (CAD): women vs men, similar between sexes

84% vs 100%

Obstructive CAD: women vs men, similar between sexes

24% vs 28%

Hemodynamically significant focal stenosis: women vs men, similar between sexes

20% vs 32%

Observational data: associations, not effects.

Further findings

ECG findings

ST-segment depression

T wave inversion

ECG findings

Similar mix of MI precipitants in both sexes

Original publication

Sex Differences in Coronary Artery Disease Characteristics Among Patients With Type 2 Myocardial Infarction. JACC Adv. Published 22 December 2023. doi:10.1016/j.jacadv.2023.100795

Composed by AI from the published abstract and checked against it. How Briefs are made →

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