Heart failure & cardiomyopathies

Feasibility and safety of endomyocardial biopsy by lumenless pacing lead sheath–directed method during cardiac implantable electronic device implantation

Heart RhythmPublished Prospective comparative study

Authors' conclusion

RV EMB by the innovative L-S-M is technically feasible and safe.

Study context

Population
Patients with an indication for a cardiovascular implantable electronic device (CIED) referred for endomyocardial biopsy (EMB)consecutive
Participants
80 patients
Exposure
Right ventricular (RV) EMB by lead sheath method vs traditional bioptome method during CIED implantation
  • Lead sheath method (L-S-M)n = 60
  • Traditional bioptome method (T-B-M)n = 20reference
Outcome
Safety and feasibility (procedural details, success rate, complications)
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

Samples per patient

L-S-M

4.1

± 0.8

T-B-M

3.8

± 0.8

Observational data: associations, not effects.

Safety

Minor complications

Transient RBBB L-S-M 3

Transient AV block L-S-M 2

Regional minor device pocket hematoma L-S-M 2

Temporary pacing for transient AV block T-B-M 1

Chest discomfort T-B-M 1

Regional hematoma T-B-M 1

Minor complications

No cardiac tamponade detected

Original publication

Feasibility and safety of endomyocardial biopsy by lumenless pacing lead sheath–directed method during cardiac implantable electronic device implantation. Heart Rhythm. Published 17 November 2024. doi:10.1016/j.hrthm.2024.11.018

Composed by AI from the published abstract and checked against it. How Briefs are made →

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