Heart failure & cardiomyopathies
Eosinophilic myocarditis: systematic review
Authors' conclusion
EMB is the mainstay for diagnostic testing for EM. CMR is potentially helpful for screening in appropriate clinical scenarios. Regarding treatment, there is no consensus regarding the optimal dosage of corticosteroids.
Study context
- Population
- Patients with eosinophilic myocarditis (EM); MEDLINE and EMBASE from inception to 10 September 2022239 articles, incl
- Participants
- 274 patients
- Comparison
- Endomyocardial biopsy (EMB)-diagnosed vs cardiac MRI (CMR)-diagnosed EM
- Outcome
- Diagnostic method
Methodological detailsPRISMA
- PRISMA
Pooled result
As reported in the abstract
Further pooled results
Presentation
- Median age (years)
- 45
- Dyspnoea
- 50.0%
- Chest pain
- 39.4%
Aetiology
- Idiopathic
- 28.8%
- Eosinophilic granulomatosis polyangiitis
- 19.3%
- Drug-induced
- 13.1%
- Hypereosinophilic syndrome
- 12.8%
Treatment
- Glucocorticoids the primary treatment, with variable dosages and regimens
Original publication
Eosinophilic myocarditis: systematic review. Heart. Published 14 November 2023. doi:10.
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