Arrhythmias & electrophysiology
Feasibility of Amulet occluder implantation after failed left atrial appendage occlusion attempt: Insights from the EMERGE LAA postapproval study
Authors' conclusion
A high degree of implantation success with a low rate of adverse events can be achieved with the Amulet occluder.
Study context
- Population
- Patients in the NCDR left atrial appendage occlusion (LAAO) Registry with an Amulet occluder implantation attempt between FDA approval (August 14, 2021) and June 30, 2023
- Participants
- 8,591 patients
- Exposure
- Amulet occluder implantation after prior failed LAAO vs index LAAO
- Prior failed LAAOn = 244
- Outcome
- Implantation success
Methodological detailsanalysis of the EMERGE LAA postapproval study, NCDR LAAO Registry
- Analysis of the EMERGE LAA postapproval study
- NCDR LAAO Registry
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Peridevice leak ≤3 mm · 45 days
- Achieved in >90% of patients in either group
Safety
Safety composite end point · 7 days or hospital discharge (whichever later)
P = 0.148
Any major adverse event · 45 days
P = 0.497
- Any major adverse event — Most adverse events similar between groups
- P > .05
Original publication
Feasibility of Amulet occluder implantation after failed left atrial appendage occlusion attempt: Insights from the EMERGE LAA postapproval study. Heart Rhythm. Published 18 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →