Aortic & peripheral vascular disease

Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population

HeartPublished prospectively enrolled general population-based cohort

Authors' conclusion

Progression of mild to moderate ascending aortic dilation was in general slow. Our findings emphasise the benefit of home BP measurements over office BP and underline the importance of BP control in subjects with a dilated ascending aorta.

Study context

Population
Subjects aged 50–65 years with ascending aortic dilation (≥40 mm) from the Swedish CArdioPulmonary bioImage Study (SCAPIS) in Linköpingsubjects with ascending aortic dilation, of 5058 enrolled in SCAPIS Linköping, 22% female, mean age 59±4 years
Participants
74 subjects
Outcome
Acute or elective aortic repair before first follow-up

Main finding

As reported in the abstract

Subjects undergoing aortic repair
Three

Observational data: associations, not effects.

Further findings

Progression rate of ascending aortic diameter · mean follow-up of 6.1±1.3 years

Mean progression rate
0.4 mm/year (range 0-1.8 mm/year)
  • Among the remaining subjects

No progression

Subjects with no progression, all men
10 (14%)

Risk factors for faster progression (multivariable analysis)

Higher 7-day home systolic blood pressure (BP) was the only factor associated with faster progression rate

Original publication

Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population. Heart. Published 13 March 2025. doi:10.1136/heartjnl-2024-325409

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