Aortic & peripheral vascular disease
Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population
Authors' conclusion
Progression of mild to moderate ascending aortic dilation was in general slow. Our findings emphasise the benefit of home BP measurements over office BP and underline the importance of BP control in subjects with a dilated ascending aorta.
Study context
- Population
- Subjects aged 50–65 years with ascending aortic dilation (≥40 mm) from the Swedish CArdioPulmonary bioImage Study (SCAPIS) in Linköpingsubjects with ascending aortic dilation, of 5058 enrolled in SCAPIS Linköping, 22% female, mean age 59±4 years
- Participants
- 74 subjects
- Outcome
- Acute or elective aortic repair before first follow-up
Main finding
As reported in the abstract
- Subjects undergoing aortic repair
- Three
Observational data: associations, not effects.
Further findings
Progression rate of ascending aortic diameter · mean follow-up of 6.1±1.3 years
- Mean progression rate
- 0.4 mm/year (range 0-1.8 mm/year)
- Among the remaining subjects
No progression
- Subjects with no progression, all men
- 10 (14%)
Risk factors for faster progression (multivariable analysis)
- Higher 7-day home systolic blood pressure (BP) was the only factor associated with faster progression rate
Original publication
Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population. Heart. Published 13 March 2025. doi:10. 1136/ heartjnl-2024-325409
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