Coronary disease & ACS

Design and rationale of aspirin versus aspirin and fondaparinux prior to early invasive strategy in patients with non-ST-elevation myocardial infarction (NSTEMI): The FOXY trial

Am Heart JPublished multicenter, open-label, noninferiority, randomized controlled trial

Study context

Population
Patients with non-ST-elevation myocardial infarction (NSTEMI) prior to invasive evaluationplanned enrolment
Participants
5,076 patients
Planned comparison
Aspirin alone is noninferior to a combination therapy with aspirin and fondaparinux
Primary endpoint
composite of:
  • 30-day mortality
  • Recurrent MI
  • Refractory ischemia
Follow-up
30-day
Methodological detailsdesign and rationale
  • Design and rationale

No results yet. This paper sets out the design of a trial; its results are to come.

Further findings

Conduct of the study

First patients enrolled in spring 2025

Original publication

Design and rationale of aspirin versus aspirin and fondaparinux prior to early invasive strategy in patients with NSTEMI: The FOXY trial. Am Heart J. Published 11 September 2025. doi:10.1016/j.ahj.2025.09.006

Composed by AI from the published abstract and checked against it. How Briefs are made →

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