Functional coronary angiography to indicate and guide revascularization in STEMI patients with multivessel disease: Rationale and design of the AIR-STEMI trial
Study context
- Population
- Patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease, after successful treatment of the culprit lesionplanned sample size (minimum)
- Participants
- 1,800 patients
- Planned comparison
- Percutaneous coronary intervention (PCI) of the nonculprit lesions guided by conventional angiography or by angiography-derived fractional flow reserve (FFR)
- Primary endpoint
- Composite of:
- All-cause death
- Any myocardial infarction (MI)
- Any cerebrovascular accident
- Any revascularization
- Follow-up
- censored once the last enrolled patient reaches 1-year follow-up
Methodological detailsrationale and design
- Rationale and design
No results yet. This paper sets out the design of a trial; its results are to come.
Further findings
Secondary endpoint: composite of cardiovascular death or myocardial infarction (MI) and each single component of the primary endpoint
- Planned; no results reported
Original publication
Functional coronary angiography to indicate and guide revascularization in STEMI patients with multivessel disease: Rationale and design of the AIR-STEMI trial. Am Heart J. Published 19 February 2025. doi:10.
Summarised from the published abstract; every number is checked against it